To understand this we should study enzymes a little more. We have already understood the idea of an 'active site'. The chemical or metabolic conversion refers to a reaction. The chemical which is converted into a product is called a 'substrate'. Hence enzymes, i.e. proteins with three dimensional structures including an 'active site', convert a substrate (S) into a product (P). Symbolically, this can be depicted as:
Which of the following statements about the nature of enzyme action are correct? S1. The substrate binds to the active site of the enzyme, altering its shape to fit more tightly. S2. Enzyme-substrate (ES) complex formation is a permanent and irreversible phenomenon. S3. Enzymes lower the activation energy of a reaction, facilitating the conversion of substrate to product. S4. After the reaction, the enzyme is altered and cannot be reused for another catalytic cycle. S5. The active site of the enzyme creates a unique microenvironment that promotes the breaking and forming of chemical bonds in the substrate.
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