Fibrinogens are needed for clotting or coagulation of blood. Globulins primarily are involved in defense mechanisms of the body and the albumins help in osmotic balance. Plasma also contains small amounts of minerals like Na+, Ca++, Mg++, HCO3-, Cl-, etc. Glucose, amino acids, lipids, etc., are also present in the plasma as they are always in transit in the body. Factors for coagulation or clotting of blood are also present in the plasma in an inactive form. Plasma without the clotting factors is called serum.
NTA tests students on the three main plasma proteins and their specific functions: fibrinogen for blood clotting, globulins for immune defense, and albumins for maintaining osmotic pressure. The common mistake is confusing these roles—students often mix up which protein does what, or forget that fibrinogen is inactive in plasma but becomes active fibrin during clotting. Remember: serum is plasma WITHOUT clotting factors, so if a question mentions serum, fibrinogen is absent. NTA frequently pairs this with questions about blood composition and the difference between plasma and serum, making it a reliable NEET topic.
This paragraph was tested 2 times in NEET.
Match the items given in Column I with those in Column II and select the correct option given below. (NEET 2018) Column I (A) Fibrinogen (B) Globulin (C) Albumin Column II (i) Osmotic balance (ii) Blood clotting (iii) Defence mechanism
Serum differs from blood in (NEET 2016 Phase 2)
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