Class 11 · Cell Cycle and Cell Division

Prophase: Chromosome Condensation — NEET Biology

✅ Asked in NEET 2017
✅ NEET 2017 PYQ

Which of the following options gives the correct sequence of events during mitosis?

QuestionNEET 2017

Which of the following options gives the correct sequence of events during mitosis?

Answer & NCERT explanation

Correct answer: A Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase

Correct mitosis sequence per NCERT: Chromosome condensation → Nuclear membrane breakdown → Chromosome alignment at equator → Centromere division → Sister chromatid segregation → Telophase. Option a includes all essential steps in proper order. Crossing over occurs in meiosis, not mitosis, making options b and d incorrect.

Read more NCERT concept on the PYQ

📖 NCERT Source

Prophase which is the first stage of karyokinesis of mitosis follows the S and G2 phases of interphase. In the S and G2 phases, the new DNA molecules formed are not distinct but intertwined. Prophase is marked by the initiation of condensation of chromosomal material. The chromosomal material becomes untangled during the process of chromatin condensation. The centrosome, which had undergone duplication during S phase of interphase, now begins to move towards opposite poles of the cell. The completion of prophase can thus be marked by the following characteristic events:

NCERT Biology · Class 11 · Chapter 10 · Paragraph 16
How NTA Uses This Concept

Prophase is the first stage of mitosis where chromosomes condense from dispersed chromatin. NTA tests this by asking what happens to chromosomal material during prophase or which organelles move during this stage. Students commonly confuse prophase with metaphase, or forget that centrosome duplication actually occurs during S phase (interphase), not prophase itself. Remember: prophase involves chromosome condensation AND centrosome movement to opposite poles; the DNA is untangling from its intertwined S/G2 state. This concept appears rarely in direct MCQs but understanding prophase events is essential for answering questions on mitotic spindle formation and chromosome behavior.

❓ Frequently Asked Questions
What does NCERT say about Prophase which first stage?
Prophase which is the first stage of karyokinesis of mitosis follows the S and G2 phases of interphase. In the S and G2 phases, the new DNA molecules formed are not distinct but intertwined.
Has this concept appeared in NEET?
Yes — appeared in NEET 2017. Describes prophase condensation sequence; other stages covered in later paras
Which chapter is this from?
Cell Cycle and Cell Division, Class 11 NCERT Biology.

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