Hormones produce their effects on target tissues by binding to specific proteins called hormone receptors located in the target tissues only. Hormone receptors present on the cell membrane of the target cells are called membrane-bound receptors and the receptors present inside the target cell are called intracellular receptors, mostly nuclear receptors (present in the nucleus). Binding of a hormone to its receptor leads to the formation of a hormone-receptor complex. Each receptor is specific to one hormone only and hence receptors are specific. Hormone-Receptor complex formation leads to certain biochemical changes in the target tissue. Target tissue metabolism and hence
Assertion (A): Hormone receptors can be located at different sites within target cells. Reason (R): All hormone receptors are membrane-bound receptors present on the cell surface.
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