Neuron Structure and Nissl's Granules — NEET Biology
✅ Asked in NEET 2018Nissl bodies are mainly composed of:
Nissl bodies are mainly composed of:
Answer & NCERT explanation
Correct answer: C — Free ribosomes and RER
Nissl bodies are specialized organelles found in neurons, composed of free ribosomes and rough endoplasmic reticulum (RER). These structures are responsible for protein synthesis in nerve cells. The ribosomes synthesize proteins needed for neuronal function, while RER helps in protein processing. Options a, b, and d are incorrect as Nissl bodies don't primarily contain lipids, DNA, or smooth ER.
Read more NCERT concept on the PYQ
A neuron is a microscopic structure composed of three major parts, namely, cell body, dendrites and axon. The cell body contains cytoplasm with typical cell organelles and certain granular bodies called Nissl's granules. Short fibres which branch repeatedly and project out of the cell body also
NTA tests your understanding of Nissl's granules as specialized rough ER in the neuronal cell body responsible for protein synthesis. Students often confuse Nissl's granules with mitochondria or think they're found throughout the entire neuron, including the axon—this is a common mistake. Remember: Nissl's granules are basophilic granular structures present only in the cell body and dendrites, NOT in the axon. They appear dark blue under the microscope due to ribosomal RNA content and are essential for synthesizing neurotransmitters and neuronal proteins. This distinction between axon (lacking Nissl's granules) and cell body/dendrites (rich in them) is frequently tested in NEET to assess your grasp of neuronal specialization.
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