Class 12 · Principles of Inheritance and Variation

Morgan's Fruit Flies and Chromosomal Theory — NEET Biology

✅ Asked in NEET 2020
✅ NEET 2020 PYQ

Experimental verification of the chromosomal theory of inheritance was done by: (NEET 2020)

QuestionNEET 2020

Experimental verification of the chromosomal theory of inheritance was done by: (NEET 2020)

Answer & NCERT explanation

Correct answer: B Morgan

T.H. Morgan experimentally verified the chromosomal theory using Drosophila (fruit flies). His linkage experiments and discovery of sex-linked inheritance provided concrete evidence that genes are located on chromosomes. Sutton and Boveri only proposed the theory, while Morgan proved it through experiments.

Read more NCERT concept on the PYQ

📖 NCERT Source

Following this synthesis of ideas, experimental verification of the chromosomal theory of inheritance by Thomas Hunt Morgan and his colleagues, led to discovering the basis for the variation that sexual reproduction produced. Morgan worked with the tiny fruit flies, Drosophila melanogaster, which were found very suitable for such studies. They could be grown on simple synthetic medium in the laboratory. They complete their life cycle in about two weeks, and a single mating could produce a large number of progeny flies. Also, there was a clear differentiation of the sexes – the male and female flies are easily distinguishable. Also, it has many types of hereditary variations that can be seen with low power microscopes.

📐See NCERT Figure 4.10 for the diagram.
NCERT Biology · Class 12 · Chapter 4 · Paragraph 59
How NTA Uses This Concept

NTA tests whether students understand why Drosophila melanogaster was chosen for genetic studies—not just what Morgan discovered, but WHY these flies were ideal. The core concept is that Morgan used fruit flies to experimentally verify that genes are located on chromosomes. Students often mistake this by confusing correlation with causation, or forgetting the practical advantages (short life cycle, large progeny, visible variations, distinct sexes). To get it right: remember the 'why' behind Drosophila selection. NEET frequently asks which organism was used and what advantages it offered—know that two-week life cycles and hundreds of offspring per mating made it perfect for tracking inheritance patterns across generations.

❓ Frequently Asked Questions
What does NCERT say about Following this synthesis ideas?
Following this synthesis of ideas, experimental verification of the chromosomal theory of inheritance by Thomas Hunt Morgan and his colleagues, led to discovering the basis for the variation that sexual reproduction produced. Morgan worked with the tiny fruit flies, Drosophila melanogaster, which were found very suitable for such studies.
Has this concept appeared in NEET?
Yes — appeared in NEET 2020. Explicitly states Morgan provided experimental verification of chromosomal theory
Which chapter is this from?
Principles of Inheritance and Variation, Class 12 NCERT Biology.

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