Class 11 · Respiration in Plants

ATP Production in Glycolysis — NEET Biology

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Can you then calculate how many ATP molecules are directly synthesised in this pathway from one glucose molecule?

NCERT Biology · Class 11 · Chapter 12 · Paragraph 16
How NTA Uses This Concept

NTA tests students' ability to calculate the net ATP molecules produced directly in glycolysis from one glucose molecule. The correct answer is 2 ATP (net), because glycolysis uses 2 ATP in the initial phase (investment phase) and produces 4 ATP in the payoff phase, giving a net of 2 ATP. The common mistake students make is forgetting that glycolysis requires an initial investment of 2 ATP molecules before any ATP is produced, or they count only the ATP produced without subtracting the ATP used. Remember: Glycolysis produces 4 ATP total but uses 2 ATP, resulting in NET 2 ATP directly from this pathway. This concept is crucial because it forms the foundation for understanding total ATP yield from one glucose molecule (including krebs cycle and ETC).

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What is the net gain of ATP when each molecule of glucose is converted to two molecules of pyruvic acid? (NEET 2022 phase 1)

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