Transferases: Group Transfer Enzymes — NEET Biology
✅ Asked in NEET 2025Transferases: Enzymes catalysing a transfer of a group, G (other than hydrogen) between a pair of substrate S and S' e.g.,
Transferases are enzymes that catalyze the transfer of functional groups (like amino, phosphate, or methyl groups) between two substrate molecules, but NOT hydrogen atoms. Students often confuse transferases with oxidoreductases, which specifically transfer hydrogen or electrons. The key distinction: transferases move non-hydrogen groups while maintaining the total number of atoms. To identify a transferase reaction correctly, look for the exchange of a chemical group between substrates and check that hydrogen transfer is not the primary mechanism. Remember that phosphorylation and transamination reactions are classic examples of transferase-catalyzed processes commonly tested in NEET.
(NEET 2025) Name the class of enzyme that usually catalyzes the following reaction: S–G + S′ → S + S′–G Where, G → a group other than hydrogen S → a substrate S′ → another substrate
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