Ligases & Bond Types Catalyzed — NEET Biology
✅ Asked in NEET 2024Ligases: Enzymes catalysing the linking together of 2 compounds, e.g., enzymes which catalyse joining of C-O, C-S, C-N, P-O etc. bonds.
Ligases are enzymes that join two compounds by forming covalent bonds like C-O, C-S, C-N, and P-O bonds. The key point NTA tests is that ligases catalyze these specific bond types—they do NOT catalyze C-C bond formation. Students often confuse this with synthetases or assume ligases can form any bond. The common mistake is forgetting that ligases require ATP and always link two substrates, while thinking they can form C-C bonds like other enzymes. Remember: ligases join compounds with energy (ATP), forming C-O, C-S, C-N, or P-O bonds specifically—not C-C bonds.
Ligases is a class of enzymes responsible for catalysing the linking together of two compounds. Which of the following bonds is not catalysed by it?
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