Ligases & Bond Types Catalyzed — NEET Biology
✅ Asked in NEET 2024Ligases is a class of enzymes responsible for catalysing the linking together of two compounds. Which of the following bonds is not catalysed by it?
Ligases is a class of enzymes responsible for catalysing the linking together of two compounds. Which of the following bonds is not catalysed by it?
Answer & NCERT explanation
Correct answer: A — C–C
Ligases typically catalyze the formation of C-O, C-N, C-S, and P-O bonds using ATP energy. However, C-C bond formation is not commonly catalyzed by ligases. C-C bonds are usually formed by other enzyme classes or through different metabolic pathways not involving ligase activity.
Read more NCERT concept on the PYQ
Ligases: Enzymes catalysing the linking together of 2 compounds, e.g., enzymes which catalyse joining of C-O, C-S, C-N, P-O etc. bonds.
Ligases are enzymes that join two compounds by forming covalent bonds like C-O, C-S, C-N, and P-O bonds. The key point NTA tests is that ligases catalyze these specific bond types—they do NOT catalyze C-C bond formation. Students often confuse this with synthetases or assume ligases can form any bond. The common mistake is forgetting that ligases require ATP and always link two substrates, while thinking they can form C-C bonds like other enzymes. Remember: ligases join compounds with energy (ATP), forming C-O, C-S, C-N, or P-O bonds specifically—not C-C bonds.
What does NCERT say about Ligases Enzymes catalysing linking?
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