Class 11 · Cell Cycle and Cell Division

Centromere Splitting in Anaphase II — NEET Biology

✅ Asked in NEET 2023
📖 NCERT Source

Anaphase II: It begins with the simultaneous splitting of the centromere of each chromosome (which was holding the sister chromatids together), allowing them to move toward opposite poles of the cell by shortening of microtubules attached to kinetochores.

NCERT Biology · Class 11 · Chapter 10 · Paragraph 42
How NTA Uses This Concept

In Anaphase II, the centromere of each chromosome splits, allowing sister chromatids to separate and move toward opposite poles. NTA tests this because it's a critical distinction from Anaphase I (where homologous chromosomes separate, not sister chromatids). Students often confuse which structures separate in which anaphase—a common trap. Remember: Anaphase I = homologous chromosomes separate; Anaphase II = sister chromatids separate after centromere splits. This concept appears frequently because understanding the difference between meiosis I and II divisions is fundamental to NEET questions on cell division and genetic variation.

Solve This NEET Question

This paragraph was tested 2 times in NEET.

Q1 of 2NEET 2023

Which of the following stages of meiosis involves division of centromere?

Q2 of 2NEET 2021

Which of the following stages of meiosis involves division of centromere?

Through deep analysis of NEET and NTA, 88 of 90 questions from the NEET 2026 paper were matched straight from the MedicNEET Biology question bank.

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of the NEET 2026 Biology paper matched from the MedicNEET question bank

MedicNEET's Biology question bank is built from the same NCERT lines NTA picks repeatedly. Not random MCQs — questions crafted exactly like NTA crafts them.

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