Class 11 · Chemical Coordination and Integration

Insulin Action on Glucose Uptake — NEET Biology

✅ Asked in NEET 2020
📖 NCERT Source

Insulin is a peptide hormone, which plays a major role in the regulation of glucose homeostasis. Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose

NCERT Biology · Class 11 · Chapter 19 · Paragraph 25
How NTA Uses This Concept

Insulin is a peptide hormone that specifically enhances glucose uptake in hepatocytes (liver cells) and adipocytes (fat cells) by promoting GLUT4 translocation to the cell membrane. Students often confuse which tissues insulin primarily acts on—remember it's mainly liver and adipose tissue, NOT muscle cells directly. Common mistakes include forgetting that insulin lowers blood glucose by increasing cellular glucose uptake and storage, not by producing glucose. To score correctly: recall that insulin promotes glycogenesis (glucose→glycogen) in liver and lipogenesis in adipose tissue, making it the primary hormone for glucose homeostasis after meals.

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QuestionNEET 2020

Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (NEET 2020)

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