Class 12 · Human Reproduction

Sperm-Ovum Fertilisation Process — NEET Biology

✅ Asked in NEET 2021
✅ NEET 2021 PYQ

Receptors for sperm binding in mammals are present on:

QuestionNEET 2021

Receptors for sperm binding in mammals are present on:

Answer & NCERT explanation

Correct answer: D Zona pellucida

Zona pellucida contains sperm binding receptors. It's the glycoprotein layer surrounding ovum where sperm recognition and binding occur during fertilization. Corona radiata is outer cell layer, perivitelline space is between zona pellucida and plasma membrane, vitelline membrane is not the primary binding site. NCERT describes zona pellucida's role in sperm-egg recognition.

Read more NCERT concept on the PYQ

📖 NCERT Source

The process of fusion of a sperm with an ovum is called fertilisation. During fertilisation, a sperm comes in contact with the zona pellucida layer of the ovum and induces changes in the membrane that block the entry of additional sperms. Thus, it ensures that only one sperm can fertilise an ovum. The secretions of the acrosome help the sperm enter into the cytoplasm of the ovum through the zona pellucida and the plasma

📐See NCERT Figure 2.10 for the diagram.
NCERT Biology · Class 12 · Chapter 2 · Paragraph 27
How NTA Uses This Concept

NTA tests whether students understand that fertilisation begins when a sperm contacts the zona pellucida (outer glycoprotein layer) of the ovum, which triggers the block to polyspermy—preventing entry of additional sperms. This ensures monogamy of fertilisation. Students often confuse whether the block occurs before or after sperm entry, or mix up which structure triggers the block. Key trap: thinking multiple sperms can fertilise one ovum, or that the block happens at the plasma membrane first. Remember: zona pellucida contact → membrane changes → polyspermy block → only one sperm enters. This concept is fundamental to understanding early embryonic development and is tested to assess reproductive biology clarity.

❓ Frequently Asked Questions
What does NCERT say about process fusion sperm with?
The process of fusion of a sperm with an ovum is called fertilisation. During fertilisation, a sperm comes in contact with the zona pellucida layer of the ovum and induces changes in the membrane that block the entry of additional sperms.
Has this concept appeared in NEET?
Yes — appeared in NEET 2021. States sperm contacts zona pellucida layer during fertilisation
Which chapter is this from?
Human Reproduction, Class 12 NCERT Biology.

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