Class 12 · Human Reproduction

Leydig Cells & Androgen Production — NEET Biology

✅ Asked in NEET 2020
📖 NCERT Source

Each lobule contains one to three highly coiled seminiferous tubules in which sperms are produced. Each seminiferous tubule is lined on its inside by two types of cells called male germ cells (spermatogonia) and Sertoli cells. The male germ cells undergo meiotic divisions finally leading to sperm formation, while Sertoli cells provide nutrition to the germ cells. The regions outside the seminiferous tubules called interstitial spaces, contain small blood vessels and interstitial cells or Leydig cells. Leydig cells synthesise and secrete testicular hormones called androgens. Other immunologically competent cells are also present.

🖼️Related NCERT figure: Diagrammatic sectional view of male pelvis showing reproductive system with labeled parts including ureter, seminal vesicle, urinary bladder, vas deferens, prostate, penis, urethra, glans penis, foreskin, testis, scrotum, bulbourethral gland, ejaculatory duct, rectum, and anus (Figure 2.1(a) Diagrammatic sectional view of male pelvis showing reproductive system)
NCERT Biology · Class 12 · Chapter 2 · Paragraph 4
How NTA Uses This Concept

Leydig cells (interstitial cells) located in interstitial spaces of the testis synthesize and secrete androgens (male hormones). Many students confuse Leydig cells with Sertoli cells—remember that Sertoli cells provide nutrition to germ cells, while Leydig cells produce hormones. This distinction is crucial for NEET questions about testicular function and endocrine roles. Key point: Leydig cells = hormone production; Sertoli cells = nutritional support. Understanding this separation helps you answer questions about male reproductive anatomy and physiology correctly.

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QuestionNEET 2020

Match the following: Match the following: Column I (a) Placenta (b) Zona pellucida (c) Bulbo-urethral glands (d) Leydig cells Column II (i) Androgens (ii) Human Chorionic Gonadotropin (hCG) (iii) Layer of the ovum (iv) Lubrication of the penis

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