tRNA Structure and Anticodon Specificity — NEET Biology
✅ Asked in NEET 2022Against the codon 5′ UAC 3′, what would be the sequence of anticodon on tRNA? (NEET 2022 Phase 2)
Against the codon 5′ UAC 3′, what would be the sequence of anticodon on tRNA? (NEET 2022 Phase 2)
Answer & NCERT explanation
Correct answer: B — 5′ AUG 3′
For codon 5′ UAC 3′, the anticodon on tRNA will be 5′ AUG 3′. Anticodons are complementary and antiparallel to codons. UAC codon pairs with GUA anticodon, but we must consider the 5′ to 3′ direction. When written in 5′ to 3′ direction, GUA becomes AUG. This follows base pairing rules: U pairs with A, A pairs with U, C pairs with G. The anticodon-codon interaction is antiparallel like DNA strands.
Read more NCERT concept on the PYQ
For initiation, there is another specific tRNA that is referred to as initiator tRNA. There are no tRNAs for stop codons. In, the secondary structure of tRNA has been depicted that looks like a clover-leaf. In actual structure, the tRNA is a compact molecule which looks like inverted L.
NTA tests whether you understand that tRNA has two critical functional regions: an anticodon loop with bases complementary to mRNA codons, and an amino acid acceptor end that binds specific amino acids. Students often mistake that all tRNAs are identical or confuse which end binds to the codon. The key trap: forgetting that tRNA specificity means each amino acid has its own tRNA, and there's no tRNA for stop codons—these are recognized by release factors instead. Remember: anticodon pairs with codon (base complementarity), amino acid end carries the correct amino acid, and initiator tRNA is special for start codons. The 3D structure is L-shaped, not just the cloverleaf you see in 2D diagrams.
What does NCERT say about For initiation there another?
Has this concept appeared in NEET?
Which chapter is this from?
Through deep analysis of NEET and NTA, 88 of 90 questions from the NEET 2026 paper were matched straight from the MedicNEET Biology question bank.
88/90MedicNEET's Biology question bank is built from the same NCERT lines NTA picks repeatedly. Not random MCQs — questions crafted exactly like NTA crafts them.