DNA Sequencing & Genome Assembly — NEET Biology
🔥 Predicted for NEET 2027The fragments were sequenced using automated DNA sequencers that worked on the principle of a method developed by Frederick Sanger. (Remember, Sanger is also credited for developing method for determination of amino acid sequences in proteins). These sequences were then arranged based on some overlapping regions present in them. This required generation of overlapping fragments for sequencing. Alignment of these sequences was humanly not possible. Therefore, specialised computer based programs were developed. These sequences were subsequently annotated and were assigned to each chromosome. The sequence of chromosome 1 was completed only in May 2006 (this was the last of the 24 human chromosomes – 22 autosomes and X and Y – to be
Adjacent to a frequently-asked paragraph in the same chapter.
How many genes are estimated to be present in the human genome?
View solution & NCERT explanation
Correct answer: A — A 20,000–25,000
HGP discovered fewer genes than expected.
What does NCERT say about fragments were sequenced using?
Has this concept appeared in NEET?
Which chapter is this from?
Through deep analysis of NEET and NTA, 176 of the 180 ReNEET 2026 (June 21) questions were already in the MedicNEET question bank before the exam.
176/180MedicNEET's Biology question bank is built from the same NCERT lines NTA picks repeatedly. Not random MCQs — questions crafted exactly like NTA crafts them.