Single Nucleotide Polymorphisms (SNPs) — NEET Biology
📚 Practice ConceptScientists have identified about 1.4 million locations where single-base DNA differences (SNPs – single nucleotide polymorphism, pronounced as 'snips') occur in humans. This information promises to revolutionise the processes of finding chromosomal locations for disease-associated sequences and tracing human history.
Which of the following statements about the Human Genome Project (HGP) and its outcomes are NOT correct? S1: The Human Genome Project was primarily a 5-year initiative aimed at exclusively sequencing the coding regions of the human DNA. S2: Expressed Sequence Tags (ESTs) represented an approach focused on identifying all genes that are transcribed as RNA. S3: One of the major findings was that approximately 99.9% of nucleotide bases are identical in all humans, highlighting minimal genetic variation. S4: Repetitive DNA sequences, which form a significant portion of the human genome, are thought to have direct coding functions. S5: The project identified approximately 1.4 million locations of Single Nucleotide Polymorphisms (SNPs), which are crucial for tracing human history and disease association.
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