Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are the two types of nucleic acids found in living systems. DNA acts as the genetic material in most of the organisms. RNA though it also acts as a genetic material in some viruses, mostly functions as a messenger. RNA has additional roles as well. It functions as adapter, structural, and in some cases as a catalytic molecule. In Class XI you have already learnt the structures of nucleotides and the way these monomer units are linked to form nucleic acid polymers. In this chapter we are going to discuss the structure of DNA, its replication, the process of making RNA from DNA (transcription), the genetic code that determines the sequences of amino acids in proteins, the process of protein synthesis (translation) and elementary basis of their regulation. The determination
Which of the above statements regarding the differences between DNA and RNA are NOT correct? S1: DNA is chemically less reactive and structurally more stable than RNA, partly due to the absence of a 2'-OH group in its sugar. S2: Both DNA and RNA are typically double-stranded molecules with similar overall helical structures. S3: DNA contains the nitrogenous base thymine, while RNA contains uracil at the corresponding position. S4: RNA is exclusively involved in protein synthesis as a messenger, adapter, and structural molecule, never acting as genetic material. S5: While both DNA and RNA can mutate, RNA mutates at a slower rate due to its less labile nature, making it a better choice for long-term genetic information storage.
Correct answer: B — S2, S4 and S5
This question examines the key structural and functional differences between DNA and RNA, as well as their implications for genetic material. S1 is correct: The NCERT states, 'Further, 2'-OH group present at every nucleotide in RNA is a reactive group and makes RNA labile and easily degradable... Therefore, DNA chemically is less reactive and structurally more stable when compared to RNA.' The presence of thymine also adds stability. S2 is NOT correct: DNA is typically double-stranded, but RNA is usually single-stranded. While RNA can form secondary structures, it's not typically a double helix like DNA. S3 is correct: The NCERT explicitly states, 'Thymine is present in DNA. Uracil is present in RNA at the place of Thymine.' S4 is NOT correct: The NCERT mentions, 'RNA though it also acts as a genetic material in some viruses, mostly functions as a messenger. RNA has additional roles as well. It functions as adapter, structural, and in some cases as a catalytic molecule.' So, RNA can act as genetic material and has multiple functions, not exclusively involved in protein synthesis or never acting as genetic material. S5 is NOT correct: The NCERT states, 'In fact, RNA being unstable, mutate at a faster rate.' DNA is preferred for storage of genetic information due to its stability, implying RNA's higher mutation rate and lability make it unsuitable for long-term storage. Therefore, statements S2, S4, and S5 are NOT correct.
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