Secondly, his concept of genes (or factors, in Mendel's words) as stable and discrete units that controlled the expression of traits and, of the pair of alleles which did not 'blend' with each other, was not accepted by his contemporaries as an explanation for the apparently continuous variation seen in nature. Thirdly, Mendel's approach of using mathematics to explain biological phenomena was totally new and unacceptable to many of the biologists of his time. Finally, though Mendel's work suggested that factors (genes) were discrete units, he could not provide any physical proof for the existence of factors or say what they were made of.
Which of the following statements are correct concerning the scientific rigor of Mendel’s experimental methodology? S1. His use of a large sampling size significantly reduced the impact of chance deviations on progeny ratios, enhancing data credibility. S2. Mendel's confirmation of inferences across successive generations ensured his results reflected general rules of inheritance. S3. He was the first to apply statistical analysis and mathematical logic to interpret biological problems. S4. By studying traits with continuous variation, Mendel could observe gradual blending of characters. S5. Mendel ensured that the factors (genes) controlling characters were treated as discrete units that did not blend.
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