Class 12 · Principles of Inheritance and Variation

Linkage & Gene Mapping — NEET Biology

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After knowing that the genes are located on the chromosomes, a good correlation was drawn between Mendel's laws: segregation and assortment of chromosomes during meiosis. The Mendel's laws were extended in the form of 'Chromosomal Theory of Inheritance'. Later, it was found that Mendel's law of independent assortment does not hold true for the genes that were located on the same chromosomes. These genes were called as 'linked genes'. Closely located genes assorted together, and distantly located genes, due to recombination, assorted independently. Linkage maps, therefore, corresponded to arrangement of genes on a chromosome.

NCERT Biology · Class 12 · Chapter 4 · Paragraph 99
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Consider chromosomal interpretation of Mendel’s results: (1) Chromosomes and genes both occur in pairs and segregate during gametogenesis. (2) Independent assortment arises from independent alignment of bivalents in meiosis I. (3) Morgan observed deviation from 9:3:3:1 when genes were on the same chromosome. (4) Such deviation is due to physical association (linkage) increasing parental combinations. (5) Therefore, independent assortment applies equally to linked genes. Which statements are correct?

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