Enzyme Catalytic Cycle & Steps — NEET Biology
📚 Practice ConceptThe catalytic cycle of an enzyme action can be described in the following steps:
Arrange the following events of an enzyme's catalytic cycle in the correct chronological sequence: (A) Substrate (S) binds to the active site of the enzyme (E). (B) The enzyme undergoes a conformational change to fit more tightly around the substrate (induced fit). (C) Formation of a transient Enzyme-Substrate (ES) complex. (D) The active site facilitates the transformation of the substrate into product(s), forming an Enzyme-Product (EP) complex. (E) Product(s) are released from the active site. (F) The free enzyme becomes available for further catalytic cycles.
View solution & NCERT explanation
Correct answer: A — A → B → C → D → E → F
The catalytic cycle of an enzyme begins with the binding of the substrate to the active site (A). This initial binding often induces a conformational change in the enzyme, allowing it to fit more tightly around the substrate, a phenomenon known as induced fit (B). This interaction leads to the formation of a transient Enzyme-Substrate (ES) complex (C). Within this complex, the active site transforms the substrate into product(s), leading to an intermediate Enzyme-Product (EP) complex (D). Subsequently, the product(s) are released from the active site (E), leaving the enzyme free and ready to bind another substrate molecule and repeat the cycle (F). This sequence accurately reflects the steps described in NCERT.
What does NCERT say about catalytic cycle enzyme action?
Has this concept appeared in NEET?
Which chapter is this from?
Through deep analysis of NEET and NTA, 176 of the 180 ReNEET 2026 (June 21) questions were already in the MedicNEET question bank before the exam.
176/180MedicNEET's Biology question bank is built from the same NCERT lines NTA picks repeatedly. Not random MCQs — questions crafted exactly like NTA crafts them.