Co-enzymes are also organic compounds but their association with the apoenzyme is only transient, usually occurring during the course of catalysis. Furthermore, co-enzymes serve as co-factors in a number of different enzyme catalyzed reactions. The essential chemical components of many coenzymes are vitamins, e.g., coenzyme nicotinamide adenine dinucleotide (NAD) and NADP contain the vitamin niacin.
Match the following types of cofactors in Column I with their characteristic features in Column II. COLUMN I (Cofactor Type) A. Prosthetic groups B. Co-enzymes C. Metal ions COLUMN II (Characteristic Feature) i. Organic compounds that associate transiently with the apoenzyme during catalysis, often derived from vitamins. ii. Non-protein constituents that form coordination bonds with enzyme's active site side chains and simultaneously with the substrate. iii. Organic compounds that are tightly bound to the apoenzyme, forming part of the active site.
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