Inspiration and expiration are carried out by creating pressure gradients between the atmosphere and the alveoli with the help of specialised muscles – intercostals and diaphragm. Volumes of air involved in these activities can be estimated with the help of spirometer and are of clinical significance.
Which of the above statements regarding the mechanism of breathing are NOT correct? S1: The contraction of diaphragm contributes to the increase in thoracic volume along the antero-posterior axis during inspiration. S2: Forceful expiration is achieved solely by the relaxation of the diaphragm and external intercostal muscles. S3: For inspiration, the intra-pulmonary pressure must become higher than the atmospheric pressure. S4: The movement of air into and out of the lungs is driven by creating a pressure gradient between the lungs and the atmosphere. S5: During normal expiration, the thoracic volume decreases due to the active contraction of internal intercostal muscles.
Correct answer: B — S2, S3 and S5
The core concept tested here is the mechanism of inspiration and expiration, including muscle actions, volume changes, and pressure gradients. S1: The contraction of diaphragm increases the volume of the thoracic chamber in the antero-posterior axis, initiating inspiration. This statement is correct. S2: Forceful expiration involves the contraction of additional muscles like the internal intercostals and abdominal muscles, which actively decrease thoracic volume beyond passive relaxation. It is not achieved solely by relaxation of the inspiratory muscles. This statement is NOT correct. S3: Inspiration occurs when the pressure within the lungs (intra-pulmonary pressure) is less than the atmospheric pressure, creating a negative pressure gradient. This statement is NOT correct. S4: The movement of air into and out of the lungs is indeed carried out by creating a pressure gradient between the lungs and the atmosphere. This statement is correct. S5: Normal expiration is a passive process resulting from the relaxation of the diaphragm and external intercostal muscles, which returns the thoracic volume to its normal position. Active contraction of internal intercostal muscles occurs during *forceful* expiration, not normal expiration. This statement is NOT correct. Therefore, statements S2, S3, and S5 are not correct. The final answer is B because S2, S3, and S5 are incorrect based on the NCERT description of breathing mechanics.
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