In animal cells, during the S phase, DNA replication begins in the nucleus, and the centriole duplicates in the cytoplasm. During the G₂ phase, proteins are synthesised in preparation for mitosis while cell growth continues.
During the S phase of interphase in animal cells, DNA replication occurs alongside centriole duplication in the cytoplasm. NTA tests this because students often confuse when centrioles duplicate (S phase, not G1 or G2) and why it matters—duplicated centrioles form the two poles of the spindle during mitosis. The common trap is thinking centrioles duplicate during G2 phase or assuming they're present in plant cells (they aren't). Remember: centrioles duplicate only in animal cells during S phase, and this is essential for spindle apparatus formation. This concept directly impacts understanding of spindle pole organization during division.
The centriole undergoes duplication during:
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