Centriole Duplication During S Phase — Parallel to DNA Replication in Nucleus
✅ Asked in NEET 2021The centriole undergoes duplication during:
The centriole undergoes duplication during:
Answer & NCERT explanation
Correct answer: A — S-phase
According to NCERT, centriole duplication occurs during S phase of interphase. This ensures that each daughter cell receives a pair of centrioles after cell division. The duplication happens simultaneously with DNA replication, not during prophase, metaphase, or G2 phase. This is crucial for proper spindle formation in subsequent mitosis.
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In animal cells, during the S phase, DNA replication begins in the nucleus, and the centriole duplicates in the cytoplasm. During the G₂ phase, proteins are synthesised in preparation for mitosis while cell growth continues.
The CELL CYCLE coordinates two crucial duplication events. During the S PHASE of interphase: (1) DNA REPLICATION begins in the NUCLEUS, doubling chromosomal content from 2C to 4C; (2) the CENTRIOLE DUPLICATES in the CYTOPLASM in parallel. Each animal cell normally has one centrosome with TWO CENTRIOLES at right angles; during S phase each centriole templates a new daughter, giving the cell TWO CENTROSOMES by the end of interphase. During the G₂ PHASE, PROTEINS are SYNTHESISED in preparation for MITOSIS while cell growth continues. By M phase, both DNA AND centrioles are duplicated, ready for distribution to two daughter cells.
NEET 2021 direct: centriole duplicates during S PHASE. Distractors: prophase (too late — by prophase, duplication is done and centrosomes are migrating to poles); metaphase (way too late — spindle is already formed); G₂ (proteins are made, but centrioles already duplicated in S). Memory rule: think of S phase as the universal 'duplication' phase — DNA + centrioles + many organelles duplicate in S. G₁ = growth; S = synthesis (duplication); G₂ = prepare for division; M = divide.
The centriole undergoes duplication during the G₂ phase or prophase of cell division.
Centriole duplicates during the S PHASE of interphase — in parallel with DNA replication. G₂ is for protein synthesis preparing for mitosis.
S phase = SYNTHESIS = DNA + centriole both DUPLICATE. G₂ = preparation phase (proteins for mitosis). Centrioles ready BEFORE prophase.
- Centriole duplicates during the S PHASE of interphase (NEET 2021).
- DNA replication also happens in S phase — DNA + centriole duplicate IN PARALLEL.
- G₂ phase: protein synthesis in preparation for mitosis; cell growth continues.
- By M phase, both DNA (2C → 4C) and centrioles (2 → 4) are duplicated, ready for distribution to daughter cells.
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