Class 11 · Chemical Coordination and Integration

Addison's Disease and Adrenal Cortex — NEET Biology

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📖 NCERT Source

Underproduction of hormones by the adrenal cortex alters carbohydrate metabolism causing acute weakness and fatigue leading to a disease called Addison's disease.

🖼️Related NCERT figure: Diagrammatic representation of adrenal gland showing: (a) adrenal gland positioned above kidney, and (b) cross-section of adrenal gland showing the outer yellow adrenal cortex and inner reddish adrenal medulla (Figure 19.4 Diagrammatic representation of : (a) Adrenal gland above kidney (b) Section showing two parts of adrenal gland)
NCERT Biology · Class 11 · Chapter 19 · Paragraph 18
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In Addison’s disease, why do patients show low blood pressure, muscle weakness and fatigue? A. Adrenal cortex fails to secrete mineralocorticoids → low Na⁺ and water B. Reduced blood volume decreases cardiac output C. Less glucose from gluconeogenesis causes low ATP for muscles D. Respiration centre decreases ventilation rate to compensate

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