Hormone Receptor Mechanisms and Signal Transduction — NEET Biology
📚 Practice ConceptHormones which interact with membrane-bound receptors normally do not enter the target cell, but generate second messengers (e.g., cyclic AMP, IP3, Ca++ etc) which in turn regulate cellular metabolism. Hormones which interact with intracellular receptors (e.g., steroid hormones, iodothyronines, etc.) mostly regulate gene expression or chromosome function by the interaction of hormone-receptor complex with the genome. Cumulative biochemical actions result in physiological and developmental effects.
Arrange the following in the correct sequence: 1. HR complex interacts with genome 2. Hormone diffuses into target cell (intracellular access) 3. Gene-expression changes → biochemical/physiological effects 4. Binding to intracellular receptor to form HR complex
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