Each myosin (thick) filament is also a polymerised protein. Many monomeric proteins called Meromyosins constitute one thick filament. Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM). The HMM component, i.e.; the head and short arm projects outwards at regular distance and angle from each other from the surface of a polymerised myosin filament and is known as cross arm. The globular head is an active ATPase enzyme and has binding sites for ATP and active sites for actin.
Assertion (A): Meromyosin has distinct structural components. Reason (R): Heavy meromyosin (HMM) forms the tail while light meromyosin (LMM) forms the globular head.
Correct answer: C — If assertion is true but reason is false.
NCERT confirms meromyosin has distinct components (Assertion true). However, NCERT states “Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM)” - HMM is the head portion, LMM is the tail, opposite to the Reason.
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