Class 11 · Locomotion and Movement

Myosin Filament Structure — NEET Biology

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Each myosin (thick) filament is also a polymerised protein. Many monomeric proteins called Meromyosins constitute one thick filament. Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM). The HMM component, i.e.; the head and short arm projects outwards at regular distance and angle from each other from the surface of a polymerised myosin filament and is known as cross arm. The globular head is an active ATPase enzyme and has binding sites for ATP and active sites for actin.

🖼️Related NCERT figure: Diagram showing (a) an actin thin filament with tropomyosin and troponin proteins wound around it, and (b) a myosin monomer (meromyosin) with labeled head, cross arm, actin binding sites, and ATP binding sites (Figure 17.3 (a) An actin (thin) filament (b) Myosin monomer (Meromyosin))
NCERT Biology · Class 11 · Chapter 17 · Paragraph 15
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Assertion (A): Meromyosin has distinct structural components. Reason (R): Heavy meromyosin (HMM) forms the tail while light meromyosin (LMM) forms the globular head.

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