Myasthenia Gravis: Autoimmune Disorder — NEET Biology

NTA tests myasthenia gravis as an autoimmune disorder that damages the neuromuscular junction, causing progressive muscle weakness and paralysis. Students often confuse it with muscular dystrophy (genetic) or forget that it's the immune system attacking acetylcholine receptors, not a problem with muscle fibers themselves. The key distinction: it's autoimmune (body attacks itself), involves neuromuscular junction dysfunction, and causes fatigue that worsens with activity. Remember: autoantibodies target ACh receptors → fewer functional receptors → weak muscle contractions → symptoms of weakness and paralysis. This concept appears frequently because it's a classic example of autoimmune disease affecting movement, bridging immunology and muscular physiology.