Microbial Sources of Drugs — NEET Biology
📚 Practice ConceptFind out the name of the microbes from which Cyclosporin A (an immunosuppressive drug) and Statins (blood cholesterol lowering agents) are obtained.
Which of the following statements regarding microbial products and their applications are correct? S1: Streptokinase, a genetically modified enzyme from *Streptococcus*, is effectively used as a 'clot buster' in patients suffering from myocardial infarction. S2: Cyclosporin A, produced by *Trichoderma polysporum*, functions as an immunosuppressive agent primarily for preventing organ rejection in transplant patients. S3: Statins obtained from the yeast *Monascus purpureus* are competitive inhibitors of the enzyme responsible for cholesterol synthesis, thus acting as blood-cholesterol lowering agents. S4: Lipases produced by microbes are incorporated into detergent formulations and are particularly helpful in clarifying bottled fruit juices. S5: The large holes characteristic of Swiss cheese are due to the extensive production of methane gas by *Propionibacterium sharmanii*.
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