Synaptic Transmission Mechanism — NEET Biology
📚 Practice ConceptGive a brief account of Mechanism of synaptic transmission.
Which of the following statements are correct regarding the mechanism of chemical synaptic transmission? S1: Chemical synapses are characterized by a fluid-filled space, the synaptic cleft, separating pre- and post-synaptic membranes. S2: Neurotransmitters are released into the synaptic cleft by the active transport mechanism across the pre-synaptic membrane. S3: The binding of neurotransmitters to specific receptors on the post-synaptic membrane always results in the generation of an excitatory potential. S4: Impulse transmission across a chemical synapse is generally slower than across an electrical synapse. S5: The binding of released neurotransmitters opens ion channels on the post-synaptic membrane, leading to ion entry and generation of a new potential.
View solution & NCERT explanation
Correct answer: B — S1, S4 and S5
The question asks for correct statements regarding chemical synaptic transmission. S1: Chemical synapses indeed have a synaptic cleft separating the pre- and post-synaptic neurons. So, S1 is correct. S2: Neurotransmitters are released into the synaptic cleft by the fusion of synaptic vesicles with the pre-synaptic membrane (exocytosis), not by active transport across the membrane. So, S2 is NOT correct. S3: The new potential developed in the post-synaptic neuron may be either excitatory or inhibitory, not always excitatory. So, S3 is NOT correct. S4: Impulse transmission across an electrical synapse is always faster than that across a chemical synapse. So, S4 is correct. S5: The binding of neurotransmitters to post-synaptic receptors opens ion channels, allowing ions to enter and thus generating a new potential. So, S5 is correct. Therefore, statements S1, S4, and S5 are correct.
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