Synaptic Transmission Mechanism — NEET Biology

Which of the following statements are correct regarding the mechanism of chemical synaptic transmission? S1: Chemical synapses are characterized by a fluid-filled space, the synaptic cleft, separating pre- and post-synaptic membranes. S2: Neurotransmitters are released into the synaptic cleft by the active transport mechanism across the pre-synaptic membrane. S3: The binding of neurotransmitters to specific receptors on the post-synaptic membrane always results in the generation of an excitatory potential. S4: Impulse transmission across a chemical synapse is generally slower than across an electrical synapse. S5: The binding of released neurotransmitters opens ion channels on the post-synaptic membrane, leading to ion entry and generation of a new potential.