Class 12 · Principles of Inheritance and Variation

Mendel's Laws of Inheritance — NEET Biology

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Based on his observations on monohybrid crosses Mendel proposed two general rules to consolidate his understanding of inheritance in monohybrid crosses. Today these rules are called the Principles or Laws of Inheritance: the First Law or Law of Dominance and the Second Law or Law of Segregation.

NCERT Biology · Class 12 · Chapter 4 · Paragraph 32
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Match the following Mendelian Laws with their key principles/cytological bases and characteristic F₂ generation ratios, assuming complete dominance: Column I (Mendel's Law) A. Law of Dominance B. Law of Segregation C. Law of Independent Assortment Column II (Key Principle/Cytological Basis) 1. Segregation of homologous chromosomes during meiosis I 2. Independent alignment of non-homologous chromosome pairs at metaphase I 3. Expression of only one trait in a heterozygous individual Column III (Associated F₂ Ratio/Pattern) I. 1:2:1 genotypic ratio II. 3:1 phenotypic ratio III. 9:3:3:1 phenotypic ratio

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Correct answer: A A-3-II, B-1-I, C-2-III

This question requires linking Mendel's laws with their underlying principles, cytological bases, and expected F2 ratios. - A. Law of Dominance: This law states that in a dissimilar pair of factors, one member dominates the other. This explains the expression of only one trait in a heterozygous individual (Column II - 3) and results in the 3:1 phenotypic ratio in the F2 generation of a monohybrid cross (Column III - II). - B. Law of Segregation: This law is based on the fact that alleles of a pair segregate from each other during gamete formation, so each gamete receives only one allele. The cytological basis for this is the segregation of homologous chromosomes during meiosis I (Column II - 1). This leads to a 1:2:1 genotypic ratio in the F2 generation of a monohybrid cross (Column III - I). - C. Law of Independent Assortment: This law states that when two pairs of traits are combined in a hybrid, segregation of one pair is independent of the other. The cytological basis is the independent alignment of non-homologous chromosome pairs at metaphase I (Column II - 2). This results in the characteristic 9:3:3:1 phenotypic ratio in the F2 generation of a dihybrid cross (Column III - III). Therefore, the correct match is A-3-II, B-1-I, C-2-III.

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Based on his observations on monohybrid crosses Mendel proposed two general rules to consolidate his understanding of inheritance in monohybrid crosses. Today these rules are called the Principles or Laws of Inheritance: the First Law or Law of Dominance and the Second Law or Law of Segregation.
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Principles of Inheritance and Variation, Class 12 NCERT Biology.

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