Chromosomal Disorders and Abnormalities — NEET Biology

Which of the following statements regarding chromosomal disorders are NOT correct? S1: Chromosomal disorders are typically determined by alteration or mutation in a single gene. S2: Aneuploidy is a condition where there is an increase in a whole set of chromosomes in an organism, often seen in plants. S3: Down's syndrome results from the gain of an extra copy of chromosome 21, leading to characteristic physical and mental retardation. S4: Individuals with Klinefelter's syndrome have a karyotype of 47, XXY, and exhibit overall masculine development with rudimentary ovaries. S5: Turner's syndrome is caused by the absence of one of the X chromosomes, resulting in a karyotype of 45, X0, and sterile females.