Class 11 · Respiration in Plants

Pyruvate Oxidative Decarboxylation — NEET Biology

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Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvic dehydrogenase. The reactions catalysed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A.

NCERT Biology · Class 11 · Chapter 12 · Paragraph 27
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Why is pyruvate dehydrogenase considered a complex enzyme?

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Correct answer: C It catalyses multiple reactions

This multi-enzyme complex carries out oxidation, decarboxylation, and transfer to CoA.

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Pyruvate, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalysed by pyruvic dehydrogenase. The reactions catalysed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A.
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Respiration in Plants, Class 11 NCERT Biology.

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