Biology · Body Fluids and Circulation · NEET
Fibrinogen is needed for clotting or coagulation of blood. Globulins are mainly involved in the defence mechanism (immunity) of the body. Albumins help in osmotic balance. This exact one-line split is straight from NCERT and is the most tested point.
Fibrinogen. During clotting, thrombin converts soluble fibrinogen into insoluble fibrin threads that form the clot. So fibrinogen is the raw material and fibrin is the product.
Albumin. It is the most abundant plasma protein and, because of its amount, it holds water in the blood and keeps the osmotic pressure of plasma. If albumin drops, fluid leaks into tissues and causes swelling (oedema).
Globulins. They include antibodies (immunoglobulins) that fight germs, so globulins are linked to the body's defence mechanism. Do not confuse them with clotting or osmotic roles.
Albumin is the most abundant plasma protein by amount. This is why it is the main protein for osmotic balance. Together fibrinogen, globulins and albumins make up about 6 to 8 percent of plasma.
Match the items given in Column I with those in Column II and select the correct option. Column I: a. Fibrinogen b. Globulin c. Albumin. Column II: (i) Osmotic balance (ii) Blood clotting (iii) Defence mechanism
Try the real previous-year questions from this chapter — each with the answer and a full solution.
Plasma proteins make up about 6 to 8 percent of plasma. The three main ones are fibrinogen, globulins and albumins.
Yes. Serum is plasma without the clotting factors, mainly fibrinogen. When blood clots, fibrinogen is used up, so the leftover fluid (serum) lacks fibrinogen. See the next concept, difference between serum and plasma.
Globulins. Antibodies are immunoglobulins, a type of globulin, which is why globulins are tied to defence.
Plasma also carries minerals, glucose, amino acids and lipids in transit, and clotting factors are present too. But for NEET, remember the three main protein functions first.
