Hardy-Weinberg Numerical Problems (p² + 2pq + q²)

Biology · Evolution · NEET

Every Hardy-Weinberg numerical uses just two equations: p + q = 1 (allele frequencies add to 1) and p² + 2pq + q² = 1 (genotype frequencies add to 1). Here p = frequency of dominant allele A, q = frequency of recessive allele a, so p² = AA, 2pq = Aa, and q² = aa. Memory hook: "APRON" — Allele frequencies (p, q) first, then Plug into the square. In NEET you are usually given one value (often q² = the recessive people who show the trait); take its square root to get q, find p = 1 − q, then square and multiply.
Hardy-Weinberg: (p + q)² = p² + 2pq + q² = 1Alleles: p = A (dominant), q = a (recessive), p + q = 1spermeggA (p)a (q)A (p)a (q)AAAapqAapqaaAA = p² (homozygous dominant)Aa = 2pq (heterozygous carrier)aa = q² (homozygous recessive)Count aa → q² → q → p → get all
A Punnett-square view of Hardy-Weinberg: crossing allele frequencies p (A) and q (a) gives genotype frequencies AA = p², Aa = 2pq (two boxes), aa = q². Since only aa individuals show the recessive trait, you read q² from the data, take its square root for q, then find p = 1 − q.

Your doubts, answered

What do p and q actually stand for in the Hardy-Weinberg equation?

In a diploid organism with two alleles at a locus, p is the frequency of the dominant allele A and q is the frequency of the recessive allele a. They are ALLELE (gene) frequencies, not people. Because these are the only two alleles, they must add up to 1: p + q = 1. NCERT says the sum total of all allelic frequencies is 1.

How do I know whether to use p², 2pq or q² for a given genotype?

p² = frequency of homozygous dominant individuals (AA). q² = frequency of homozygous recessive individuals (aa). 2pq = frequency of heterozygous individuals (Aa). The '2' in 2pq is there because a heterozygote can form two ways (A from mother and a from father, or a from mother and A from father). NCERT: 'AA is p², aa is q², Aa is 2pq, hence p²+2pq+q²=1.'

Why do most numericals start by taking the square root of q²?

Because the only people you can spot by looking are the homozygous recessive ones (aa) — they SHOW the recessive trait (like a disease). That count gives you q² directly. Take its square root to get q, then p = 1 − q. Once you have p and q you can find every genotype frequency. Heterozygotes (Aa) look like AA, so you can never count them directly — you must calculate 2pq.

If the frequency of allele A is 0.1, what is the frequency of AA?

AA = p². Here p (frequency of A) = 0.1, so AA = (0.1)² = 0.01. Students wrongly pick 0.10 by forgetting to square. This is exactly the ReNEET 2026 question. Also note q = 1 − 0.1 = 0.9, aa = q² = 0.81, and Aa = 2pq = 2 × 0.1 × 0.9 = 0.18. Check: 0.01 + 0.18 + 0.81 = 1.

A disease appears in 1 out of 100 people. What is the carrier (heterozygote) frequency?

The 1 in 100 showing the recessive disease are aa, so q² = 1/100 = 0.01. Then q = √0.01 = 0.1 and p = 1 − 0.1 = 0.9. Carriers are heterozygotes = 2pq = 2 × 0.9 × 0.1 = 0.18, i.e. 18 in 100. So carriers are far more common than affected people — a favourite NEET twist.

⚠️ The NEET trap
Frequency of allele A is 0.1, so frequency of AA individuals is also 0.1.
AA = p², so AA = (0.1)² = 0.01, not 0.1. Allele frequency and genotype frequency are different — you must square p to get the AA genotype frequency.
🧠 NTA loves giving you the ALLELE frequency (p) and asking for the GENOTYPE frequency (p²). Never quote p as the answer — always square it. Same for q → q².

Real NEET questions

2026

A population of diploid organisms is at Hardy–Weinberg equilibrium. If the frequency of allele A is 0.1, the frequency of AA is ________.

A · 0.01
B · 0.02
C · 0.10
D · 0.99
Solution: Under Hardy-Weinberg equilibrium the frequency of homozygous dominant AA is p², where p is the frequency of allele A. Here p = 0.1, so AA = (0.1)² = 0.01. Trap: choosing 0.10 (the allele frequency itself) instead of squaring it.
2016

In Hardy-Weinberg equation, the frequency of heterozygous individual is represented by

A ·
B · 2pq
C · pq
D ·
Solution: In the expansion p² + 2pq + q² = 1, heterozygotes (Aa) are 2pq, homozygous dominant (AA) is p², and homozygous recessive (aa) is q². 'pq' alone is not a term in the binomial expansion of (p + q)², so it is wrong.

Solved Evolution NEET PYQs

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Frequently asked

What are the only two equations I need for Hardy-Weinberg numericals?

p + q = 1 and p² + 2pq + q² = 1. The first relates the two allele frequencies; the second relates the three genotype frequencies. Every NEET numerical is solved by combining these.

Which genotype frequency can I read directly from the data?

Only q² (the homozygous recessive aa), because those individuals actually show the recessive trait and can be counted. From q² you get q, then p, then everything else.

Does the total population size matter in these problems?

No. Hardy-Weinberg deals in frequencies (proportions between 0 and 1), not counts. If they give you numbers of people, convert to a fraction of the total first.

Can two dominant-looking people have a recessive child, and does that break the equation?

Yes — two Aa (dominant-looking) parents can have an aa child. It does not break the equation; heterozygotes (2pq) carry the hidden recessive allele, which is why carriers are often more common than affected individuals.

Is p always the dominant allele?

By NCERT convention p is the frequency of allele A (dominant) and q of allele a (recessive), but the maths works either way as long as you stay consistent. Read the question to see which allele's frequency is given.