NEET 2023 Phase 1 · ChemistryNucleic acidsPrevious Year Question

Given below are two statements: Statement I: A unit formed by the attachment of a base to the 1' position of sugar is known as a nucleoside. Statement II: When a nucleoside is linked to phosphorous acid at the 5'-position of the sugar moiety, we get a nucleotide. In the light of the above statements, choose the correct answer from the options given below:

Answer: (C) Statement I is true but Statement II is false. \textbf{Answer:} (C) Statement I is true, but a nucleotide forms with phosphoric acid (not phosphorous acid), so Statement II is false.

  1. A.Both Statement I and Statement II are true
  2. B.Both Statement I and Statement II are false
  3. C.Statement I is true but Statement II is false
  4. D.Statement I is false but Statement II is true

Correct Answer

(C) Statement I is true but Statement II is false

Solution & Explanation

\textbf{Answer:} (C) Statement I is true, but a nucleotide forms with phosphoric acid (not phosphorous acid), so Statement II is false. \textbf{Solution:} Statement I is correct: attaching a nitrogenous base to the 1' position of the pentose sugar gives a nucleoside. Statement II is wrong: a nucleotide is formed when the nucleoside is esterified at the 5'-position with phosphoric acid , not phosphorous acid . Hence Statement I is true but Statement II is false, giving option C.

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