Tissue Analysis: Acid-Soluble Pool — NEET Biology
📚 Practice ConceptWe can continue asking in the same way, what type of organic compounds are found in living tissues? How to analyse? Analyse a living tissue by grinding it in trichloroacetic acid using a mortar and a pestle. We can take any living tissue (a vegetable or a piece of liver, etc.) and grind it in trichloroacetic acid (Cl3CCOOH) using a mortar and a pestle. We obtain a thick slurry. If we were to strain this through a cheesecloth or cotton we would obtain two fractions. One is called the filtrate or more technically, the acid-soluble pool, and the second, the retentate or the acid-insoluble fraction. Scientists have found thousands of organic compounds in the acid-soluble pool.
Assertion (A): Tissue grinding separates cellular components into different fractions. Reason (R): The acid-insoluble fraction contains small molecules while the acid-soluble pool contains large molecules.
View solution & NCERT explanation
Correct answer: C — If assertion is true but reason is false.
The Assertion is true as NCERT describes tissue grinding creating fractions. However, NCERT states “One is called the filtrate or more technically, the acid-soluble pool, and the second, the retentate or the acid-insoluble fraction” where acid-soluble contains small molecules and acid-insoluble contains large molecules - the Reason reverses this relationship.
What does NCERT say about We can continue asking?
Has this concept appeared in NEET?
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Through deep analysis of NEET and NTA, 88 of 90 questions from the NEET 2026 paper were matched straight from the MedicNEET Biology question bank.
88/90MedicNEET's Biology question bank is built from the same NCERT lines NTA picks repeatedly. Not random MCQs — questions crafted exactly like NTA crafts them.