Transgenic animals are also used to understand how genes contribute to the development of a disease by serving as models for human diseases, such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer's.
Match the following Columns I, II, and III based on the applications of transgenic animals: Column I A. Mouse models B. Rosie Cow C. Increased sensitivity to toxic substances D. Transgenic mice Column II i. Human alpha-lactalbumin ii. Polio vaccine safety iii. Cancer, cystic fibrosis, Alzheimer’s iv. Faster evaluation of drug effects Column III p. Vaccine safety testing q. Study of human diseases r. Biological product synthesis s. Chemical safety testing
Correct answer: D — A-iii-q, B-i-r, C-iv-s, D-ii-p
Let's match each row: A. Mouse models are used as models for human diseases like cancer, cystic fibrosis, and Alzheimer’s (A-iii-q). B. Rosie Cow produced human alpha-lactalbumin, which is a biological product (B-i-r). C. Transgenic animals with increased sensitivity to toxic substances allow faster evaluation of drug effects, which is part of chemical safety testing (C-iv-s). D. Transgenic mice are used for testing the safety of vaccines, specifically the polio vaccine (D-ii-p). Therefore, the correct match is A-iii-q, B-i-r, C-iv-s, D-ii-p. Tested Concept: Specific examples and categories of applications of transgenic animals.
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