Class 12 · Biotechnology and Its Applications

Oral Protein Pharmaceuticals — NEET Biology

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Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?

NCERT Biology · Class 12 · Chapter 10 · Paragraph 75
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Which of the following statements correctly highlight the advantages and features related to insulin therapy? S1. Insulin extracted from the pancreas of slaughtered animals is structurally identical to human insulin. S2. Recombinant DNA technology ensures that therapeutic drugs like insulin are free from immunological responses when derived from non-human sources. S3. The primary challenge in producing recombinant human insulin was assembling the A and B chains into a mature, active form. S4. Orally administered insulin is generally not effective due to the protein's digestion by gastrointestinal enzymes. S5. Eli Lilly's method for recombinant insulin involved producing pro-insulin in E. coli, followed by its maturation.

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