Bioprocess engineering: Maintenance of sterile (microbial contamination-free) ambience in chemical engineering processes to enable growth of only the desired microbe/eukaryotic cell in large quantities for the manufacture of biotechnological products like antibiotics, vaccines, enzymes, etc.
Consider the following statements about genetic engineering and bioprocess engineering: 1. Genetic engineering is concerned with altering DNA or RNA and introducing it into host organisms to change their phenotype. 2. Bioprocess engineering provides sterile conditions to grow only desired microbes or eukaryotic cells in large quantities. 3. The three fundamental steps of genetic modification are: identifying desirable DNA, introducing it into the host, and ensuring its maintenance and inheritance. 4. Genetic engineering is mainly focused on maintaining sterile industrial conditions for large-scale product manufacture. 5. Bioprocess engineering is unrelated to the production of antibiotics, vaccines, or enzymes.
Correct answer: A — 1, 2 and 3 are correct
Statement 1 is correct: Genetic engineering alters the chemistry of genetic material to change host phenotype. Statement 2 is correct: Bioprocess engineering maintains sterile conditions for large-scale growth of desired cells. Statement 3 is correct: Genetic modification always requires identification, introduction, and maintenance of DNA. Statement 4 is incorrect: Large-scale industrial culturing belongs to bioprocess engineering, not genetic engineering. Statement 5 is incorrect: Bioprocess engineering is directly used to manufacture antibiotics, vaccines, and enzymes.
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