Spindle Fibres & Kinetochores — NEET Biology
✅ Asked in NEET 2024Spindle fibers attach to kinetochores of chromosomes during:
Spindle fibers attach to kinetochores of chromosomes during:
Answer & NCERT explanation
Correct answer: B — Metaphase
Spindle fibres attach to kinetochores during metaphase when chromosomes align at the cell's equator. Kinetochores are assembled during prophase, but actual attachment and proper alignment occur in metaphase. This attachment is crucial for proper chromosome segregation. During prophase, kinetochores form but attachment is still establishing. In anaphase, fibres pull chromosomes apart, and in telophase, spindle apparatus disassembles. The stable attachment ensuring proper segregation occurs specifically in metaphase.
Read more NCERT concept on the PYQ
• Spindle fibres attach to kinetochores of chromosomes.
Spindle fibres attach to kinetochores (specialized protein structures on centromeres) during metaphase to pull sister chromatids apart. Students often confuse kinetochores with centromeres—remember that kinetochores are protein complexes assembled ON the centromere where spindle fibres actually attach. The key trap: assuming spindle fibres connect directly to the chromosome DNA itself rather than specifically to kinetochore proteins. To ace this, memorize: kinetochores are the attachment sites, not the centromere itself. This concept appears in NEET because understanding chromosome segregation mechanisms is fundamental to cell division.
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