What is the average cell cycle span for a mammalian cell? 2. Distinguish cytokinesis from karyokinesis. 3. Describe the events taking place during interphase. 4. What is G0 (quiescent phase) of cell cycle?
Arrange the following events of the interphase in a typical eukaryotic cell cycle in their correct chronological order. 1. Continuous cell growth and normal metabolic activity. 2. Centriole duplication in animal cells. 3. DNA synthesis leading to doubling of DNA content. 4. Synthesis of proteins necessary for spindle formation. 5. Interval after M phase and before S phase. 6. Cell growth continues in preparation for mitosis.
Correct answer: A — 5, 1, 2, 3, 6, 4
This question requires arranging key events of interphase (G₁, S, G₂) in their chronological order. Interphase consists of G₁, S, and G₂ phases in that sequence. - G₁ phase (Gap 1) is the interval between mitosis and the initiation of DNA replication. During this phase, the cell is metabolically active and continuously grows. - S phase (Synthesis) is when DNA replication occurs, doubling the DNA content. In animal cells, centriole duplication also occurs during S phase. - G₂ phase (Gap 2) is when proteins are synthesized in preparation for mitosis, and cell growth continues. Let's map the given events to their respective phases: 1. Continuous cell growth and normal metabolic activity: G₁ phase (occurs throughout G₁). 2. Centriole duplication in animal cells: S phase (occurs in cytoplasm during S phase). 3. DNA synthesis leading to doubling of DNA content: S phase (the defining event of S phase). 4. Synthesis of proteins necessary for spindle formation: G₂ phase (proteins for mitosis are synthesized). 5. Interval after M phase and before S phase: G₁ phase (This precisely defines G₁). 6. Cell growth continues in preparation for mitosis: G₂ phase (cell growth continues in G₂). Chronological order of events: - First, the cell is in G₁ phase: Events 5 and 1 happen (5 defines the period, 1 describes activity). So, 5 then 1. - Next, the cell enters S phase: Events 2 and 3 happen (2 is centriole duplication, 3 is DNA synthesis). So, 2 then 3. - Finally, the cell enters G₂ phase: Events 6 and 4 happen (6 is continued growth, 4 is protein synthesis for mitosis). So, 6 then 4. The correct chronological order is 5, 1, 2, 3, 6, 4.
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