Class 11 · Cell Cycle and Cell Division

Mitosis vs Meiosis Key Differences — NEET Biology

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List the main differences between mitosis and meiosis.

NCERT Biology · Class 11 · Chapter 10 · Paragraph 55
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Which of the following statements are correct concerning the comparison between mitosis, meiosis I, and meiosis II? S1. Both mitosis and meiosis II are equational divisions, separating sister chromatids and generally maintaining the chromosome number of the parent cell (for that specific division). S2. Meiosis I is unique among these divisions for undergoing synapsis, crossing over, and the separation of homologous chromosomes, leading to reduction in chromosome number. S3. Interkinesis, which precedes Meiosis II, is a brief interphase-like stage where significant cell growth and DNA replication occur to prepare for the second meiotic division. S4. While mitosis can occur in both haploid and diploid cells, meiosis (both I and II) is typically restricted to diploid cells destined to form gametes. S5. The alignment of chromosomes at the equatorial plate in Metaphase I involves bivalent structures, whereas in Metaphase II and mitotic metaphase, individual chromosomes with two chromatids align.

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Correct answer: B S1, S2, S4, and S5 are correct

Let's evaluate each statement: S1. Correct. Mitosis is known as an equational division, separating sister chromatids and maintaining the chromosome number. Meiosis II also separates sister chromatids and maintains the haploid chromosome number (n) inherited from Meiosis I. Therefore, both are equational divisions. S2. Correct. Meiosis I is a reductional division characterized by synapsis of homologous chromosomes, crossing over between non-sister chromatids, and the separation of homologous chromosomes, which reduces the chromosome number by half. S3. Incorrect. Interkinesis is the stage between Meiosis I and Meiosis II. It is generally short-lived, and critically, there is no replication of DNA during interkinesis. While some cell growth might occur, significant DNA replication does not. S4. Correct. Mitosis can occur in both haploid and diploid cells (e.g., male honey bees, and plants generally). Meiosis, being a reductional division leading to gamete formation, is indeed restricted to diploid cells. S5. Correct. In Metaphase I, homologous chromosomes paired as bivalents align at the equatorial plate. In contrast, during Metaphase II and mitotic metaphase, individual chromosomes (each still consisting of two sister chromatids) align at the equator. Therefore, statements S1, S2, S4, and S5 are correct, while S3 is incorrect.

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List the main differences between mitosis and meiosis.
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Cell Cycle and Cell Division, Class 11 NCERT Biology.

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