Can there be mitosis without DNA replication in 'S' phase?
Arrange the following events in the correct sequence as they occur in a typical eukaryotic cell cycle leading to division: A. Synthesis of proteins in preparation for mitosis. B. Duplication of centrioles in the cytoplasm. C. Division of cytoplasm into two daughter cells. D. Chromosomal material condenses and mitotic spindle formation initiates. E. Cell is metabolically active and continuously grows without DNA replication. F. Alignment of chromosomes at the equatorial plate.
Correct answer: A — E → B → A → D → F → C
The core concept tested is the sequential order of events and phases in a typical eukaryotic cell cycle. Let's identify the phase for each event: E. Cell is metabolically active and continuously grows without DNA replication: This describes the G1 phase. B. Duplication of centrioles in the cytoplasm: This occurs during the S phase. A. Synthesis of proteins in preparation for mitosis: This occurs during the G2 phase. D. Chromosomal material condenses and mitotic spindle formation initiates: This is characteristic of Prophase (part of M phase). F. Alignment of chromosomes at the equatorial plate: This is characteristic of Metaphase (part of M phase). C. Division of cytoplasm into two daughter cells: This is Cytokinesis, which typically follows karyokinesis (Telophase) and completes the M phase. The correct sequence of phases in a cell cycle is G1 → S → G2 → M (Prophase → Metaphase → Anaphase → Telophase) → Cytokinesis. Therefore, the correct sequence of events is E (G1) → B (S) → A (G2) → D (Prophase) → F (Metaphase) → C (Cytokinesis).
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