Class 11 · Cell: The Unit of Life

Membrane Proteins: Integral vs Peripheral — NEET Biology

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Depending on the ease of extraction, membrane proteins can be classified as integral and peripheral. Peripheral proteins lie on the surface of membrane while the integral proteins are partially or totally buried in the membrane.

🖼️Related NCERT figure: Detailed diagram of cell membrane structure showing phospholipid bilayer with embedded proteins. Shows peripheral proteins on the surface, integral proteins embedded in the membrane, sugar molecules attached to proteins, and cholesterol molecules within the phospholipid bilayer. The phospholipids are arranged with hydrophilic heads facing outward and hydrophobic tails inward. (Figure 8.4 Fluid mosaic model of plasma membrane)
NCERT Biology · Class 11 · Chapter 8 · Paragraph 36
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Assertion (A): Membrane proteins can be classified based on their association with the membrane. Reason (R): Peripheral proteins are partially or totally buried in the membrane while integral proteins lie on the surface of membrane.

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