As a result, there is a rapid movement of glucose from blood to hepatocytes and adipocytes resulting in decreased blood glucose levels (hypoglycemia). Insulin also stimulates conversion of glucose to glycogen (glycogenesis) in the target cells. The glucose homeostasis in blood is thus maintained jointly by the two – insulin and glucagons.
Which of the following statements correctly describes the interplay of hormones in maintaining blood glucose homeostasis? S1: Insulin promotes hyperglycemia by increasing glucose synthesis in the liver. S2: Glucagon stimulates gluconeogenesis and glycogenolysis, both contributing to increased blood glucose. S3: The glucose homeostasis in blood is maintained jointly by insulin and glucagon. S4: A deficiency of glucagon would lead to prolonged hyperglycemia and formation of ketone bodies. S5: Insulin reduces cellular glucose uptake, whereas glucagon enhances it.
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