Nephron Function & Filtrate Reabsorption — NEET Biology
📚 Practice ConceptJGA, a specialised portion of the nephrons, plays a significant role in the regulation of GFR. Nearly 99 per cent reabsorption of the filtrate takes place through different parts of the nephrons. PCT is the major site of reabsorption and selective secretion. HL primarily helps to maintain osmolar gradient (300 mOsmolL⁻¹ - 1200 mOsmolL⁻¹) within the kidney interstitium. DCT and collecting duct allow extensive reabsorption of water and certain electrolytes, which help in osmoregulation; H⁺, K⁺ and NH₃ could be secreted into the filtrate by the tubules to maintain the ionic balance and pH of body fluids.
Assertion (A): The juxtaglomerular apparatus is important for kidney function regulation. Reason (R): JGA plays a significant role in the regulation of GFR.
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