Reabsorption of water from distal parts of the tubules is facilitated by hormone _______.
Which of the following statements regarding the regulation of kidney function are NOT correct? S1: A fall in GFR activates the JG cells to release renin, which subsequently increases sodium excretion. S2: Angiotensin II causes vasodilation and thus decreases glomerular blood pressure and GFR. S3: Aldosterone, released from the adrenal cortex, promotes the reabsorption of Na+ and water from the distal parts of the tubule. S4: Atrial Natriuretic Factor (ANF) acts as a check on the renin-angiotensin mechanism by causing vasoconstriction and increasing blood pressure. S5: Antidiuretic Hormone (ADH) facilitates water reabsorption from the latter parts of the tubule, thereby preventing diuresis.
Correct answer: C — S1, S2 and S4
The question asks to identify the statements that are NOT correct regarding the regulation of kidney function. S1: "A fall in GFR can activate the JG cells to release renin..." Renin ultimately leads to the release of aldosterone, which "causes reabsorption of Na+ and water from the distal parts of the tubule," thus increasing sodium retention, not excretion. So, S1 is not correct. S2: "Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR." The statement says it causes vasodilation and decreases BP and GFR, which is incorrect. So, S2 is not correct. S3: "Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule." So, S3 is correct. S4: "ANF can cause vasodilation... and thereby decrease the blood pressure. ANF mechanism, therefore, acts as a check on the renin-angiotensin mechanism." The statement says ANF causes vasoconstriction and increases blood pressure, which is incorrect. So, S4 is not correct. S5: "ADH facilitates water reabsorption from latter parts of the tubule, thereby preventing diuresis." So, S5 is correct. Therefore, statements S1, S2, and S4 are NOT correct. Final Answer: The final answer is C
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