Class 12 · Molecular Basis of Inheritance

Gene Size Variation and Dystrophin — NEET Biology

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The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases.

NCERT Biology · Class 12 · Chapter 5 · Paragraph 142
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Match the following genomic features with their associated values/properties: Column I (a) Chromosome 1 gene count (b) Chromosome Y gene count (c) Total estimated human genes (d) Average human gene size (e) Length of dystrophin gene Column II (i) 231 genes (ii) 2968 genes (iii) 3000 bases (iv) 20,000–25,000 genes (v) 2.4 million bases

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Correct answer: D (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii), (e)-(v)

This question requires matching specific numerical and descriptive features of the human genome as identified by the Human Genome Project. Let's match each item: (a) Chromosome 1 gene count: Chromosome 1 has the most genes, specifically 2968. So, (a)-(ii). (b) Chromosome Y gene count: The Y chromosome has the fewest genes, with 231. So, (b)-(i). (c) Total estimated human genes: The total number of genes in the human genome is estimated at 20,000–25,000. So, (c)-(iv). (d) Average human gene size: The average gene consists of 3000 bases. So, (d)-(iii). (e) Length of dystrophin gene: The largest known human gene is dystrophin, at 2.4 million bases. So, (e)-(v). Thus, the correct combination is (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii), (e)-(v).

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The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases.
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Molecular Basis of Inheritance, Class 12 NCERT Biology.

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