Class 12 · Molecular Basis of Inheritance

Human Genome: Gene Count & DNA Similarity — NEET Biology

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📖 NCERT Source

The total number of genes is estimated at 30,000–much lower than previous estimates of 80,000 to 1,40,000 genes. Almost all (99.9 per cent) nucleotide bases are exactly the same in all humans.

NCERT Biology · Class 12 · Chapter 5 · Paragraph 143
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Assertion (A): All nucleotide bases are exactly the same in all humans. Reason (R): The 0.1% variation in human DNA sequences forms the basis of DNA fingerprinting.

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Correct answer: D If the assertion is false but the reason is true.

NCERT states “Almost all (99.9 per cent) nucleotide bases are exactly the same in all humans” - the Assertion removes the qualifier making it false. NCERT explains that the remaining 0.1% variation is what makes DNA fingerprinting possible, making the Reason true. This tests understanding that genetic variation exists despite high similarity.

❓ Frequently Asked Questions
What does NCERT say about total number genes estimated?
The total number of genes is estimated at 30,000–much lower than previous estimates of 80,000 to 1,40,000 genes. Almost all (99.9 per cent) nucleotide bases are exactly the same in all humans.
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Which chapter is this from?
Molecular Basis of Inheritance, Class 12 NCERT Biology.

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