Class 12 · Molecular Basis of Inheritance

Unknown Gene Functions & Genomic Mystery — NEET Biology

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The functions are unknown for over 50 per cent of the discovered genes.

NCERT Biology · Class 12 · Chapter 5 · Paragraph 144
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Which of the following statements about the Human Genome Project (HGP) are NOT correct? S1: The HGP was a 13-year project aimed at sequencing 3.3 billion base pairs, completed in 2003. S2: The estimated cost for sequencing the human genome was approximately 9 billion US dollars, based on the cost per base pair. S3: A primary goal of the HGP was to understand human biology and apply knowledge to solve challenges in health care and agriculture. S4: Functions of less than 50% of the discovered genes were known at the time of project completion. S5: Chromosome Y was found to have the fewest genes, while chromosome 1 had the most genes among all human chromosomes.

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Correct answer: D All are correct

Let's evaluate each statement regarding the Human Genome Project: S1: The project was a 13-year project, started in 1990 and completed in 2003, aiming to sequence 3.3 billion base pairs. This statement is correct. S2: With 3 x 10^9 bp and an estimated cost of US $3 per bp, the total estimated cost was 9 billion US dollars. This statement is correct. S3: Goals of HGP included understanding human biology and applying knowledge to health care, agriculture, energy production, and environmental remediation. This statement is correct. S4: The salient features of the human genome project state that 'The functions are unknown for over 50 per cent of the discovered genes.' Therefore, stating that functions of *less than 50%* were known is correct as functions for *over 50%* were unknown. This statement is correct. S5: Chromosome 1 has most genes (2968), and the Y has the fewest (231). This statement is correct. Thus, all are correct Final Answer: The final answer is D as all are correct.

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The functions are unknown for over 50 per cent of the discovered genes.
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Molecular Basis of Inheritance, Class 12 NCERT Biology.

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